Module · physiology

Bioenergetics: ATP-PC, glycolytic, oxidative systems

60 min Lesson phy-01
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What you'll learn

Where the ATP comes from

Every muscle contraction costs one molecule of ATP. Your body stores almost none of it. Instead, three systems regenerate ATP at different speeds and durations. Knowing which system fuels which activity is the difference between programming that works and programming that doesn't.

ATP-PC (phosphagen) system

This is why a heavy single feels totally different from a set of 12. Different fuel.

Glycolytic (anaerobic glycolysis) system

The 'burn' isn't lactate — it's hydrogen ion accumulation lowering pH. Lactate is actually a fuel the body uses.

Oxidative (aerobic) system

Programming consequences

If you're training strength (ATP-PC system): rest 2–5 min between sets. Anything less and you're under-recovered for the next max effort. If you're training hypertrophy (glycolytic + some ATP-PC): rest 60–90 seconds. The metabolic stress is part of the adaptation. Longer rest = less hypertrophy stimulus. If you're training muscular endurance (glycolytic + oxidative): rest 30–60 seconds. You're teaching the body to clear waste products and keep working. If you're training aerobic capacity (oxidative): keep the heart rate elevated for the entire session. Zone 2 work (60–70% max HR) is the gold standard.

Common programming mistakes

1. Resting 30 seconds between heavy singles. You're now training glycolytic capacity, not max strength. 2. Resting 4 minutes between hypertrophy sets. You're losing the metabolic stress stimulus. 3. Calling everything 'HIIT'. True HIIT = work intervals at 90%+ HR with structured rest. Most 'HIIT' classes are just glycolytic conditioning.

What to know cold

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